Pharmacology of Blood and Inflammation Important MCQ Points
|Pharmacology of Blood and Inflammation Important MCQ Points by Dr. Moneeb for UHS , KMUĀ , Bolan Medical College , Bahria and other Medical Universities Students.
Blood Pharmacology Important MCQs
Only LDL increased …..>> Statins
Only triglycerides increased ….>>>>>> Fibrates
HDL decreased VLDL increased LDL increased …… >>Niacin
Phytosterols increased …..>>>Ezetimibe
Statins …. >>>>Rhabdomyolysis
Resins…>>>> Decrease vit K absorption
Niacin contraindicated in gout patient
Niacin releases …. >>>>Histamine
Fibrates …. >>>>Gall stones
Heparin … Activation of antithrmbin III …. Fast onset used in emergency iv …. Not IM coz hematoma formation. Is there…monitored by aptt….. Antidote protamine sulphate….. Chemical antagonism
In pregnancy …. Heparin is safe but warfarin is teratogenic
Warfarin for chronic use …. Oral route … Inhibits Vitamin K epoxide reductase…. Monitored by pt…. Antidote for chronic is vit K but for acute bleeding fresh frozen plasma
If heparin induced thrombocytopenia … Use direct thrombin inhibitors
Most common adverse ffevts by heparin warfarin ….. Bleeding
Platelet agreegation inhibitors useful for arterial thrombi
Disopyramide shows coronary steal phenomenon
Abciximab is a monoclonal antibody and irreversibly blocks IIb/IIIa receptors
Stretokinase …. Hypersensitivity reactions
Use stretokinase within 3 to 6 hours
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