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Important OSPE questions for Physiology 1st year MBBS UHS

Q1:Which Blood Group is Universal donor and recipient ?

Ans : Donor O-Blood Group

Recepient : AB+ blood group

Q2:Which condition is produced in Rh+ blood group in a fetus mother having Rh- blood group in second pregnancy?

Ans:Erythroblastosis foetalis

Q3:identify the apparatus?

Ans: Wester Green Apparatus

Q4:Name the two physiological conditions in which ESR is hIgh?

Ans: a) Pregnancy

b) Mensturation

c)Increased temp.

Q5:Identify the apparastus?

Ans: Westergens Tube with stand

Q6:Give one cause of Microcytic anemia?

Ans:Deficiency of Vit B12 ( folic acid)

Q7:Write down contents of Haemy`s fluid?

Ans: Disteled water


Q8: Name the areas in the body where reproduction of RBCs take place?

Ans : Yolk sac,liver . spleen, lymph node,bone marrow

Q9: Identify the apparatus?

Ans: Syphmomanaometer

Q10: What is the effect of moderate exercise on systolic blood ptressure?

Ans: Systolic blood pressure increases

Q11: Which nervous mechanism increases blood pressure during exercise?

Ans: Symptahtic over stimulation

Q12:Enumerate two methods of recording blood pressure?

Ans:Auscaltatory method

Palpatory method

Q13: What is rouleax formation?

Ans:Pilling up of cells one upon another because their density is  more than plasma is called rouleax formation

Q14:Name two pathological conditions in which ESR is raised?

Ans: Acute Infections:

Choronic infections


Q15: Name the two conditions in which Leucocytes count increases

Ans : Appendicitis , Tonsilitis , Pnemonia

Q16: What is the mean corpuscular Hb concentration?

Ans:It is the average Hb conc. Inerthyrocytes

MCHC=Hb gram/100ml —-    PCV/100ml     * 100

Q17:What is the clinical significance of MCHC?

Ans:If MCHC less than 32, the RBC is hypochromic and it is present in iron deficiency anemia and thalasemia

Q18: What is FEVI %

Ans: It is the percentage of vital capacity which is expired in fst second of expiration

Q19: In what type of disese it is increased?

Ans: It is increased in Obstructive Lung Disease .

Q20: What produces 1st heart sound?

Ans: Closure of Mitral and Tricuspid valves line in less 5th intercostals space

Q21: In which area apex beat is examined ?

Ans : About 9 cm  from midline or 1 cm internal to midclavical .

Q22: Name the conditions In which clotting time is increased ?

Ans: Haemophilia A , B,Vit deficiency and liver disease and Throbocytopenia

Q23: What is normal clotting time?

Ans:2-6 mins capillary method

Q24: How will you charge Neubaurs Chamber?

Ans: a) Clean the Neubaur Chamber

B)Fix the Nuebar chamber on the stage with clips and place coverslip over it

c)Now take the prepared RBC/WBC pipette and touch the tip of the pipette  near the edge coverslip on central plat form at an angle of 45 degrees and drop wise drop the fluid

d)The fluid enters the below the coverslip because the capillary action immediately removes the pipette

Q25:Write the contents of Haeym`s fluid?

Ans :  NaCl



Distilled Water

Q26: Prepare the blood smear on a slide for DLC count.

Q27:Name the conditions in which the neutrophils are increased ?

Ans: Acute pyrogenic infections ,Abscess,Boils and tonsilits

Q28: Write two functions of platelets ?


Coagulation and Clot retraction

Q29: why the Leshman stain be acetone free?

Ans: Acetone causes shrinkage of cells and may cause lysis of cells

Q30: what type of image do you observe in the microscope ?

Ans : Eye Piece forms vertical ,erect and enlarged image.

Q31: name the antigen on RBC and agglutinin in the plasma of patient with O blood group?

Ans:  Antigen ….>None       ,     Agglutinin …..>  Anti A  and Anti B

Q32:What is the genotype and phenotype of the above patient?

Ans: Phenotype O , Genotype  OO

Q33:How will you charge the Westergen Tube?

Q34:Give any two physiological conditions in which ESR is raised?

Ans: Pregnancy , Menstruration , Increased Temp and High in females

Q35: Why and how many times the blood is diluted to count red blood cells ?

Ans: The No of RBCs is very high so blood is diluted 200 times with diluents

Q36: Give two pathological factors causing polycythemia?

Ans: Hypoxia  , polycythemia vera