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Important Biochemistry OSPE Questions for 1st year MBBS


1)      Q1: Which two sugars are more sweeter  than glucose?

2)      Q2: Write down products of oxidation and reduction of glucose?

3)      Q3: In which condition C-reactive protein is increased? Ans Hepatoglobin

4)      Q4:In Electrophoresis which two proteins are obtained before albumin?

5)      Q5:Which lipids are present in inner mitochondrial membrane? Which control fluidity of membrane?

6)      In which two conditions glucose is appear in urine?

7)      Give rmp of centrifuge machine and give time for which clotted blood is centrifuged?

8)      How will you prepare 4ml of normal saline solution from 1% NaOH?

9)      How will you differentiate between reducing and non reducing sugars?

10)   How will you find out protein in urine without using any reagent?

11)   Differentiate b/w cystine and cystiene?

12)   Write difference b/w creatine and creatinine ?

13)   Why polysaccharide are not digested in body?

14)   What are protamines?

15)   Why Amino acids are abundant in protamines?

16)   What is iodine test?

17)   What is millon test?

18)   Why biurette is group test for ptoteins?

19)   What are abnormal constituents of proteins?

20)   Difference b/w dextrin and dextran?

21)   What is hypersensitivity syndrome ? What are its signs?

22)   Name two phospholipids present in outer leaflet of plasma membrane?

23)   Name two non reducing disaccharides?

24)   Name the electrodes for pH meter?

25)   Prepare 2 ml solution of 1% normal saline?

26)   Name two monovalent cations in urine ?

27)   Perform Iodine test.

28)   Perform the test for the presence of chloride in the urine.

29)   What is normal plasma glucose in fasting?

30)   Name two plasma proteins present in excretion of heme and hemoglobin.

31)   What is level of total plasma proteins?

32)   Name the condition in which plasma protein levels are increased without affecting the A:G ratio?

33)   Name two sources of ammonia in our body.

34)   What is normal urea concentration in plasma?

35)   Where are plasma immnoglobullins are synthesized?

36)   Name types of light chains found in immunoglobulins.

37)   Guanido acetic acid is formed in which organ and fom which two standard amino acids?

38)   Give four conditions in which hypocalcemia may develop?

39)   Which is the major protein of human plasma and what is its normal conc.?

40)   How are free fatty acids (or non estrified amono acids) transported in blood?

41)   In which four conditions hypercholesterolemia may seen?

42)   Which keto acid is formed by the transamination of aspartate catalyzed by AST?

43)   Name any two conditions in which elevated AST activity may be observed in plasma ?

44)   What is kernicterus?

45)   Which apolipoprotein is present in VDL and LDL but not in HDL?

46)   Which is the main apolipprotein of HDL?

47)   How many isozymes of HDL are formed in the body?

48)   LDH requires which co-enzyme?

49)   Elevated plasma alkaline phosphatase activity is observed in which two conditions physiologically?

50)   Which keto acid is formed by the transaminition of aspartate catalyzed by AST?

51)   What are the precautions are to take before the oral glucose tolerance test?

52)   What is the color of biliverdin?

53)   Which enzyme catalyzes the heme to biliverdin?

54)   How  much urea may be excreted in urine daily by a normal adult subject?

55)   Blood urea is increased in which disease of organ?

56)   Degradation of heme to biliverdin releases which gas?

57)   Calcium exists in which form in blood plasma?

58)   Name the isozymes of creatine kinase?

59)   What is the significane of CK-MB?

60)   Bile salts and bile pigments are seen in excess quantities in urine in which condition?

61)   What is the principle function of  cholestryl ester transfer protein CETP?

62)   What is normal uric acid level in blood?

63)   What is the effect of organic aids on serum uric acid level?